San Luis Obispo, Left: In a cozy cluster of more than 30 wineries, Peloton Cellars and Sinor-LaVallee are nearest the water. Use Slo Wine Country's interactive map to plan your adventure.
Humboldt, Right: Briceland Vineyards' award-winning wines (and charming digs) are well worth the twisty drive from Highway 101; 707-923-2429.
San Luis Obispo, Left: Alice Waters protégé Brian Collins is lighting up the scene at Ember, his off-the-beaten-path spot with a wood-fired grill that highlights local bounty; 805-474-7700.
Humboldt, Right: Folie Douce pours from local wineries and pulls from local waters, like Humboldt Bay oysters with horseradish, lemon sorbet, and edible flowers; 707-822-1042.
San Luis Obispo, Left: Guadalupe/Nipomo Dunes are perfect for windswept strolling (and played the sands of Egypt in the film The Ten Commandments).
Humboldt, Right: You could spend a week roaming redwood country, but if you're tight for time, check out Elk Prairie and Gold Bluffs Beach, both in Prairie Creek Redwoods State Park.
San Luis Obispo, Left: SummerWood Winery & Inn has a demonstration kitchen and offers 20% off for wine club members. Rates start at $300; 805-227-1111.
Humboldt, Right: The lovely Carter House Inns also has a great restaurant that features Humboldt County wines. Rates start at $209; 800-404-1390.