This gastro-cantina fuses all things local with Mexican-style heat. 3926 30th St., 619/291-1859 or eltakeiteasy.com.
Vin de Syrah
At cocktail time, this swanky wine bar is sublime-both for quaff and a light snack. 901 5th Ave., 619/234-4166 or syrahwineparlor.com.
Craft & Commerce
This Little Italy spot specializes in comfort food with a twist. Think hot dogs topped with toasted sesame seeds and yuzu kosho mayo (pictured). 675 W. Beech St., 619/269-2202 or craft-commerce.com.
Nine-Ten has a loyal following and a reputation for fresh, seasonal fare. 910 Prospect St., 858/964-5400 or nine-ten.com.